The study is called PRINCIPLE. It is run by the University of Oxford, and is funded by the UK government as a national priority study.

The study aims to find treatments that reduce hospital admission and speed recovery for people with symptoms of COVID-19.

People included in the study must be aged over 65, or aged 50-64 with underlying health conditions. They will either receive usual care, or usual care plus a study drug. All study drugs are widely used to treat other conditions and have been assessed as being safe for use in this study. As many people as possible who join the study will also be tested for COVID-19.

If you have symptoms of COVID-19 (a new or worsening continuous cough and/or a high temperature), and have had them for less than 15 days, you may be able to take part in this study.

Please see www.phctrials.ox.ac.uk/principle-trial for full details of this study.
If you have any questions, or do not have internet access, please call the PRINCIPLE study team on 0800 138 0880.

If you’d like to know more about COVID 19 research and how you can contribute, please visit the Be Part of Research site, www.bepartofresearch.nihr.ac.uk, which is run by the National Institute for Health Research.

We are pleased to be supporting this important research, as we urgently need to find effective, early treatments for COVID-19 that can be used in the community.

So, please make contact if you have symptoms of COVID-19 and are aged over 65, or aged 50-64 with underlying health conditions!